I. Analytical Method for Guanidino Compounds. - New high-speed fully automated guanidino compound analyzer. - Automatic guanidine analyzer using benzoin as a fluorogenic reagent. - Simple methods for the determination of methylguanidine and guanidinosuccinic acid in biological fluids. - Enzymic determination of methylguanidine in urine. - II. Metabolism of Guanidino Compound in Normal and Abnormal Organs and in Metabolic Diseases. - Developmental changes in guanidino compounds levels in mouse organs. - Developmental changes of guanidino compounds in chick embryo. - Metabolism of L-(amidino-15N)-arginine to guanidine compounds. - Biosynthesis of guanidinoacetic acid in isolated rat hepatocytes. - Biosynthesis of guanidinosuccinic acid in isolated rat hepatocytes: evaluation of guanidine cycle and acidosis. - The role of the liver as a significant modulator of the serum guanidinoacetic acid level in man. - Conversion of urea nitrogen into protein nitrogen by a freshwater fish sarotherodon mossambicus. - Topographical distribution of sheep brain arginase: its response to some guanidino compounds. - The effects of sodium valproate on blood ammonia levels and the concentrations of guanidino compounds in mouse tissue. - The guanidine cycle. - Arginine utilization in muscle and kidney of frog during ammonotoxemia. - Arginine metabolism in citrullinemic patients. - Studies on the occurrence of guanidino compounds in serum and urine of patients with epilepsy neuronal ceroid-lipofuscinosis and uremic patients. - Determination of guanidino compounds in plasma and urine of patients with argininemia before and during therapy. - Hyperargininemia: treatment with sodium benzonate and phenylacetic acid. - III. Physiological Pharmacological and Toxicological Aspects of Guanidino Compound. - Effect of methylguanidine on muscle protein synthesis. - Effect of methylguanidine on erythrocyte membranes. - Taurine and the actions of guanidinoethane sulfonate. - Effects of guanidinoethane sulfonate and taurine on electroshock seizures in mice. - Effect of taurine taurocyamine and anticonvulsants on dibenzoylguanidine-induced convulsions and their relation to brain monoamine levels in ddY and El mice. - Effect of chronic alcohol administration on the concentrations of guanidino compounds in rat organs. - IV. Involvement of Guanidino Compound in Acute and Chronic Renal Faiure. - Guanidino compounds: Implications in uremia. - A study of creatine metabolism in chronic renal failure rats. - Guanidino compounds in patients with acute renal failure. - Possibility of a common metabolic pathway for the production of methylguanidine and dimethylamine in chronic renal failure. - Guanidinoacetic acid (GAA) in patients with chronic renal failure (CRF) and diabetes mellitus (DM). - Metabolic changes of guanidino compounds in acute renal failure complicated with hepatic disease. - Urinary guanidinoacetic acid excretion in gentamicin nephrotoxicity. - The importance of energy intake for preventing accumulation of guanidino compounds in patients with chronic renal failure. - The effect of lactulose on the metabolism of guanidino compounds in chronic renal failure. - Evaluation of the efficacy of anti-rejection therapy using the quantitative analysis of guanidinoacetic acid (GAA) urinary excretion as a guide. - Metabolic profiles of guanidino compounds in various tissues of uremic rats. - Guanidinoacetic acid (GAA) deficiency and supplementation in rats with chronic renal failure (CRF). - V. Natural Guanidino Compounds: A Review. - Natural guanidino compounds. - Participants. - Index: Guanidines in Organs. Language: English